The band joined forces with a host of UK YouTube and Vine stars in aid of Red Nose Day.
Bethan Mary Leadley, Doug Armstrong, Luke Cutforth, Ebony Day and Quinn Humphreys are among the online creators to have been enlisted by The Brett Domino Trio to help make a charity single for Red Nose Day.
The musical duo were tasked with creating the song to raise money for Comic Relief, with the YouTubers and Viners providing vocals and appearing in the accompanying video. You can watch the result below.
Red Nose Day (which will be held this Friday, 13 March) is a biennial fundraising event for Comic Relief which provides support across the UK and Africa for those less fortunate. In previous years this has included helping to fund the creation of schools and providing clean drinking water in Africa, and donations to charities that aid those with mental and physical disabilities here in the UK.
You can donate £3 by texting 70703.
To find out more about the work Comic Relief do, and what else is happening for Red Nose Day, click here.
This isn’t the first time YouTubers have appeared on a charity single, with Zoe Sugg, Joe Sugg and Alfie Deyes singing on Band Aid 30 last year.
Brett and Bethan also featured as part of our article, imagining what it might be like if YouTubers remade Band Aid.
For updates follow @TenEightyUK on Twitter or TenEighty UK on Facebook.