Jack and Dean become the second guest presenters of the new Dan and Phil show on BBC Radio 1.
Jack and Dean first gained radio airplay for their song Consent on The Matt Edmondson Show earlier this year.
The comedy duo also recently featured on The Scott Mills Show, playing Innuendo Bingo in the studio.
The new Internet Takeover show is available on the BBC Radio 1 website.
Read our feature interview with Jack and Dean: Jokers With Heart, find out more about the Internet Takeover on BBC Radio 1 or read about YouTube gamers featuring in a BBC Radio 1 documentary.